JCGG Symposia
Research Network

JCGG Office:
Systems Glycobiology Research Group,
RIKEN Global Research Cluster
2-1 Hirosawa Wako-shi,
Saitama 351-0198, JAPAN
Tel: +81(48)467-9613,
Fax: +81(48)462-4692

JCGG Symposia

The 4th Symposium of Japanese Consortium for Glycobiology and Glycotechnology

Integration from functional analyses of sugar chains to systems glycobiology
October 23 - 24, 2006 Tokyo Conference Center (Shinagawa)
program October 23 (Monday), 2006
9:30-9:35 Opening Address
Yoshitaka Nagai (President, JCGG)
9:35-9:45 Guest Lecture
The 20th anniversary of RIKEN Frontier Research System
Kohei Tamao (RIKEN)
9:45-10:30 Invited Lecture
Chairperson : Akemi Suzuki (RIKEN)

Molecular Mechanisms of Membrane Trafficking and Protein Sorting
Akihiko Nakano (RIKEN)
10:30-10:45  Coffee Break
Chairperson : Yasunori Kozutsumi (RIKEN)
10:45-12:00 ◊ Approach from membrane microdomain

Heterogeneity of lipid rafts
Toshihide Kobayashi (RIKEN)

Lipid rafts formation by glucosylated lipids and neuronal functions
Yoshio Hirabayashi (RIKEN)

Glycolipid-Mediated Axon Quidance
Hiroyuki Kamiguchi (RIKEN)
12:00-12:10  Break
12:10-13:00 JCGG Lunchon Seminer 1 (Immuno-Biological Laboratories Co., Ltd)
Metabolic regulation of amyloid β peptide and Alzheimer's disease
Takaomi Saido (RIKEN)
13:00-13:10   Break
Chairperson : Toshihide Kobayashi (RIKEN)
13:10-14:00 ◊ Processing of glycoproteins

Pathophysiology of glycosyltransferase processing by Alzheimer's β-secretase
Yasuhiro Hashimoto (RIKEN)

Synthetic chemistry and glycobiology: Toward understanding the glycoprotein processing mechanism
Yukishige Ito (RIKEN)
Chairperson : Yoahio Hirabayashi (RIKEN)
14:00-14:50 ◊ Cell migration and organogenesis

Glycosylation of an ADAMTS protease essential for cell migration in C. elegans
Kiyoji Nishiwaki (RIKEN)

Aberrant migration of the precursors of the vagus motor neurons in the mutant zebrafish embryos defective in the protein modification by fucosylation
Hitoshi Okamoto (RIKEN)
14:50-15:05  Coffee Break
Chairperson : Hironobu Hashimoto (NIAD-UE)
15:05-16:35 ◊ Immune functions

Expression analysis of glycochain-related genes using correlation index-based DNA microarray
Yasunori Kozutsumi (Kyoto University)

NKT cell activation and immunotherapy by α-galactosylceramide
Masaru Taniguchi (RIKEN)

Role of glycan signals in humoral immune responses
Takeshi Tsubata (Tokyo Medical Dental University)

Generation and analysis of siglec-1+ macrophage depletion mice
Yasunobu Miyake (RIKEN)
Chairperson : Toshisuke Kawasaki (Ritsumeikan University)
16:35-17:25 ◊ Clinical and industrial applications

Clinical significances of AFP-L3% (fucosylated AFP)
Shinji Satomura (Wako Co.)

Development and application of trehalose: Fom basic research to business
Shigeharu Fukuda (Hayashibara Co.)
17:25-17:35 Glycoscience in RIKEN
Tomoya Ogawa (RIKEN)
17:40-19:40  Banquet
program October 24 (Tuesday), 2006
9:30-9:40 Opening address
Mext "Glycomics" project: Attainment and perspective
Koichi Furukawa (Nagoya University)
Chairperson : Tamao Endo (Tokyo Metropolitan Institute of Gerontology)
9:40-10:30 ◊ Regulation of signaling

Towards integrated understanding of signal regulation mechanisms with glycosylation
Koichi Furukawa (Nagoya University)

Function of Notch signaling in somitogenesis via glycosylation
Yumiko Saga (National Institute of Genetics)
10:30-10:45  Coffee Break
Chairperson : Yukishige Ito (RIKEN)
10:45-12:25 ◊ Advances in structural analysis

The structure and function of a glycosidase analyzed by ultra-high resolution crystallography
Hiroaki Kato (Kyoto University)

Significance of glycosylation analysis in cell therapy and challenges to characterization of cellular therapy products based on glycosylation
Nana Kawasaki (National Institute of Health Science)

Structural Characterization of Protein and Carbohydrates Using MALDI-MSn
Koichi Tanaka(Shimadzu Co.)

Structural characterization of glycopeptides and glycosphingolipids by mass spectrometry
Minoru Suzuki (RIKEN)
12:25-13:35   Break
12:25-13:25 JCGG Lunchon Seminer 2 (Shimadzu Co.)

MS imaging of glycolipid
Mitsutoshi Seto (IMS)

Post-translational modification analysis of a cryoglobulin derived from a myeloma patient using mass spectrometry
Masaki Yamada (Shimadzu Co.)
13:25-13:35   Break
Chairperson :
Naoyuki Taniguchi
(Osaka University)
Sumihiro Hase (Osaka University)
13:35-14:50 ◊ Nuero-muscular functions

A carbohydrate binding protein, Galectin-1, promotes proliferation of adult neural stem cells
Hideyuki Okano (Keio University)

The function of the HNK-1 carbohydrate
Shogo Oka (Kyoto University)

Protein O-mannosylation and α-dystroglycanopathies
Tamao Endo (Toyko Metropolitan Institute of Gerontology)
14:50-15:05  Coffee Break
Chairperson : Koji Kimata (Aichi Medical University)
15:05-16:45 ◊ Extracellular matrices

Polysialic acid: its frequent occurrence, structural diversity and functions
Ken Kitajima (Nagoya University)

Customization of the extracellular microenvironment and an emerging concept of matriome
Kiyotoshi Sekiguchi (Osaka University)

Formation of the tumor angiogenic microenvironment by hyaluronan-rich matrix
Naoki Itano (Shinshu University)

A role for oligosaccharide-based signaling in tumor invasion and metastasis
Michinari Hamaguchi (Nagoya University)
16:45-16:55 Closing Remarks
Akemi Suzuki (Organizer, Chairman)