International Symposium on ER stress, glycosylation, homeostasis and diseases

International Symposium on ER stress, glycosylation, homeostasis and diseases

Date
March 22 (Thu) - 23 (Fri), 2018
Venue
Suzuki Umetaro Hall, RIKEN (Wako)
2-1, Hirosawa, Wako, Saitama 351-0198, Japan
Organizer
Tadashi Suzuki (RIKEN)
Speaker
Jeffrey L. Brodsky (Univ. Pittsburgh)
Reid Gilmore (Univ. Massachusetts)
Yoshio Hirabayashi (RIKEN)
Nobuko Hosokawa (Kyoto Univ.)
Yukishige Ito (RIKEN)
Yasuhiro Kajihara (Osaka Univ.)
Daisuke Kohda (Kyushu Univ.)
Gerardo Z. Lederkremer (Tel Aviv Univ.)
Maurizio Molinari (IRB Bellinzona)
Kazutoshi Mori (Kyoto Univ.)
Hitoshi Nakatogawa (Tokyo Inst. Technol.)
Tadashi Suzuki (RIKEN)
Tomohiko Taguchi (Univ. Tokyo)
Supported by
The Japanese Biochemical Society
RIKEN
Mizutani Foundation for Glycoscience
Japan Consortium for Glycobiology and Glycotechnology

Registration Closed

Program

March 22 (Thu)
09:00-09:10 Opening remarks
09:10-09:50
Keynote Lecture (1)

J. Brodsky (Univ. Pittsburgh, USA)

Protein Conformational Diseases and Endoplasmic Reticulum Associated Degradation: Lessons from Model Systems and Therapeutic Strategies
09:50-10:10 Coffee Break
10:10-10:40

D. Kohda (Kyushu Univ.)

Integrative Structural Biology Approach to Understand the Structural and Dynamic Basis of Asn-Glycosylation
10:40-11:10

R. Gilmore (Univ. Massachusetts, USA)

Glycosylation assembly lines to maximize N-glycosylation efficiency
11:10-11:30 Coffee Break
11:30-12:00

Y. Hirabayashi (RIKEN)

Membrane glycolipid synthesis and ER-stress
12:00-12:30

T. Taguchi (Univ. Tokyo)

Exocytic trafficking of STING, an innate immunity signaling protein, from the ER
12:30-14:00 Lunch Break
14:00-14:30

Y. Ito (RIKEN)

Analysis of ER glycoprotein processing events by means of chemical synthesis
14:30-15:00

Y. Kajihara (Osaka Univ.)

Chemical synthesis of homogeneous misfolded glycoproteins for understanding glycoprotein quality control system
15:00-15:30

N. Hosokawa (Kyoto Univ.)

ERp46 triggers mannose-trimming activity of EDEM3
15:30-17:50 Poster Session  - 3F Lobby -
18:00- Get Together Party  - Hirosawa Club -
March 23 (Fri)
09:00-9:40
Keynote Lecture (2)

K. Mori (Kyoto Univ.)

Mechanistic analysis of mammalian ER-associated degradation
09:40-10:00 Coffee Break
10:00-10:30

G. Lederkremer (Tel Aviv Univ., Israel)

The cellular mechanism for timing of glycoprotein folding quality control
10:30-11:00

T. Suzuki (RIKEN)

Is NGLY1-deficiency a result of defective ER-associated degradation?
11:00-11:20 Coffee Break
11:20-11:50

M. Molinari (IRB Bellinzona, Switzerland)

Clearance of Proteasome-resistant protein aggregates from the endoplasmic reticulum
11:50-12:20

H. Nakatogawa (Tokyo Inst. Technol.)

Molecular mechanisms underlying autophagic degradation of the ER
12:20-12:30 Closing Remarks

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